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My Result Is Uncertain

As a starting point for an important conversation with your doctor, click on the name of the test you were given to learn more about the results.

My test was Comprehensive BRACAnalysis^®

Comprehensive BRACAnalysis^®

Comprehensive BRACAnalysis^® tests for mutations in the BRCA1 and BRCA2 genes associated with hereditary breast and ovarian cancer (HBOC) syndrome.

My result is Genetic Variant of Uncertain Significance

On to "Uncertain: What does my result mean?"

"If the test shows a change in BRCA1 or BRCA2 that has not been associated with cancer in other people, that person's test result may be interpreted as ambiguous or uncertain. One study found that 10 percent of women who underwent BRCA1 and BRCA2 testing had this type of ambiguous genetic change."

- National Cancer Institute, National Institutes of Health

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