BRACAnalysis® can only be ordered by a qualified healthcare professional.
Join the Conversation

Positive: What Does My Result Mean?

Positive for a Deleterious Mutation: Overview

If your test result is either "Positive for a Deleterious Mutation" or "Suspected Deleterious":

  • You have a mutation or alteration in either the BRCA1 and BRCA2 gene
  • You have hereditary breast and ovarian cancer (HBOC) syndrome
  • HBOC syndrome increases the risk of various cancers, primarily breast and ovarian cancer
  • While the risk of developing these cancers is high, not everyone with HBOC syndrome will develop cancer

Your Cancer Risks

If You Have NOT Had Breast
or Ovarian Cancer:
Mutation Carrier General Population
Breast cancer by age 50 33%-50% 2%
Breast cancer by age 70 56%-87% 7%
Ovarian cancer by age 70 27%-44% <2%
Male breast cancer by age 70 6% .05%
If You HAVE Had Breast
or Ovarian Cancer:
Mutation Carrier General Population
Ovarian cancer 15% not available
Breast cancer after 5 years 27% 3.5%
Breast cancer by age 70 64% 11%
Other Cancer Risks:* Mutation Carrier General Population
Prostate cancer by age 80 20% 15%
Pancreatic cancer by age 80 2%-4% <1%

* Less information is available about the risks of these and other cancers than about breast and ovarian cancers.

On to "Positive: What Should I Do Now?"

"Because everyone has genetic alterations that do not increase the risk of disease, it is sometimes not known whether a specific change affects a person's risk of developing cancer. As more research is conducted and more people are tested for BRCA1 or BRCA2 alterations, scientists will learn more about these genetic alterations and cancer risk."

- National Cancer Institute, National Institutes of Health

Women Share Their Stories

Watch BRAC Video Watch BRAC Video