BRACAnalysis® can only be ordered by a qualified healthcare professional.
Join the Conversation

Positive: What Does My Result Mean?

Positive for a Deleterious Mutation: Overview

If your test result is either "Positive for a Deleterious Mutation" or "Suspected Deleterious":

  • You have a mutation or alteration in either the BRCA1 and BRCA2 gene
  • You have hereditary breast and ovarian cancer (HBOC) syndrome
  • HBOC syndrome increases the risk of various cancers, primarily breast and ovarian cancer
  • While the risk of developing these cancers is high, not everyone with HBOC syndrome will develop cancer

Your Cancer Risks

If You Have NOT Had Breast
or Ovarian Cancer:
Mutation Carrier General Population
Breast cancer by age 50 33%-50% 2%
Breast cancer by age 70 56%-87% 7%
Ovarian cancer by age 70 27%-44% <2%
Male breast cancer by age 70 6% .05%
If You HAVE Had Breast
or Ovarian Cancer:
Mutation Carrier General Population
Ovarian cancer 15% not available
Breast cancer after 5 years 27% 3.5%
Breast cancer by age 70 64% 11%
Other Cancer Risks:* Mutation Carrier General Population
Prostate cancer by age 80 20% 15%
Pancreatic cancer by age 80 2%-4% <1%

* Less information is available about the risks of these and other cancers than about breast and ovarian cancers.

On to "Positive: What Should I Do Now?"

"A woman who tests positive can consider taking the drug tamoxifen, which has been found to reduce the risk of developing breast cancer by almost 50 percent in women at high risk."

- The National Human Genome Research Institute, National Institutes of Health

Women Share Their Stories

Watch BRAC Video Watch BRAC Video